If you are taking naproxen and find it is not working very well for you, you may like to try a different NSAID.

Gross GJ, Moore J (July 2004). "Effect of COX-1/COX-2 inhibition versus selective COX-2 inhibition on coronary vasodilator responses to arachidonic acid and acetylcholine". Pharmacology. 71 (3): 135–42. doi: 10.1159/000077447. PMID 15161995. S2CID 34018223. Other drugs are available to treat your condition. Some may be more suitable for you than others. Examples include: a b c d Rodrigues AD (November 2005). "Impact of CYP2C9 genotype on pharmacokinetics: are all cyclooxygenase inhibitors the same?". Drug Metabolism and Disposition. 33 (11): 1567–75. doi: 10.1124/dmd.105.006452. PMID 16118328. S2CID 5754183. Talk to your doctor if you're unsure how long you need to take naproxen for. If you forget to take it Naproxen may reduce the blood pressure-lowering effects of blood pressure medications. This may occur because prostaglandins play a role in the regulation of blood pressure.

Who may not be able to take naproxen

If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: As with other non- COX-2 selective NSAIDs, naproxen can cause gastrointestinal problems, such as heartburn, constipation, diarrhea, ulcers and stomach bleeding. [21] Naproxen should be taken orally with, or just after food, to decrease the risk of gastrointestinal side effects. [22] Persons with a history of ulcers or inflammatory bowel disease should consult a doctor before taking naproxen. [22] In U.S. markets, naproxen is sold with boxed warnings about the risk of gastrointestinal ulceration or bleeding. [1] Naproxen poses an intermediate risk of stomach ulcers compared with ibuprofen, which is low-risk, and indometacin, which is high-risk. [23] To reduce stomach ulceration risk, it is often combined with a proton-pump inhibitor (a medication that reduces stomach acid production) during long-term treatment of those with pre-existing stomach ulcers or a history of developing stomach ulcers while on NSAIDs. [24] [25] Cardiovascular [ edit ] Naproxen may increase the blood levels of lithium (Eskalith, Lithobid) by reducing the excretion of lithium by the kidneys. Increased levels of lithium may lead to lithium toxicity.

Naproxen has been industrially produced by Syntex starting from 2-naphthol as follows: [40] "Pope-Peach" should read " Pope- Peachey" Society and culture [ edit ] Brand names [ edit ]Naproxen sodium is available as both an immediate release and as an extended release tablet. The extended release formulations (sometimes called "sustained release", or "enteric coated") take longer to take effect than the immediate release formulations, and therefore are less useful when immediate pain relief is desired. Extended release formulations are more useful for the treatment of chronic, or long-lasting, conditions, in which long-term pain relief is desirable. [15] Ask your doctor before using an antacid, and use only the type your doctor recommends. Some antacids can make it harder for your body to absorb naproxen. Naproxen side effects Laryngitis is an inflammation of the larynx. Inflammation of the larynx is most often caused by viral infections. Symptoms include sore throat, cough, problems swallowing, and fever. The voice changes produced by laryngitis may last after the fever and other symptoms of the acute infection have gone away. The best natural home remedy to relieve pain and other symptoms caused by laryngitis includes resting your voice and breathing humidified air often. Turning on the hot water in the bathroom and then sitting in the steam can soothe and relieve laryngitis symptoms. Acetaminophen (Tylenol) and anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil, Aleve) can relieve pain and inflammation caused by laryngitis. Don't give children aspirin to infants, toddlers, children, and teens because of the risk of developing Reye's syndrome, which can be fatal. Home remedies like resting your voice and sitting in humidified air can cure laryngitis. Medications like anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil, Aleve) and acetaminophen (Tylenol) can relieve and soothe pain and symptoms caused by laryngitis. The initial dose is 550 mg, followed by 275 mg every 6 to 8 hours or 550 mg every 12 hours as needed. Do not use this medicine in the setting of heart bypass surgery (coronary artery bypass graft, or CABG).